|
|
2,3-dihydroxy-3-methylpentanoate <=> 3-methyl-2-oxopentanoate + H2O
|
4.2.1.9
dihydroxy-acid dehydratase
|
–
|
| |
BRENDA:
BS18755
|
|
|
|
acetyl-CoA + pyruvate + H2O <=> H+ + (R)-citramalate + CoA
|
2.3.1.182
(R)-citramalate synthase
2.3.3.13
2-isopropylmalate synthase
|
–
–
|
| |
BRENDA:
BR48833
KEGG:
R07399
MetaCyc:
RXN-7743
SABIO-RK:
9043
|
|
|
|
2-aceto-2-hydroxybutyrate + NADPH <=> 2,3-dihydroxy-3-methylpentanoate + NADP+
|
1.1.1.86
ketol-acid reductoisomerase (NADP+)
|
–
|
| |
BRENDA:
BS383015
|
|
|
|
ATP + 2-methylbutanoate + CoA <=> ADP + phosphate + 2-methylbutanoyl-CoA
|
6.2.1.13
acetate---CoA ligase (ADP-forming)
6.2.1.B11
|
–
–
|
| |
BRENDA:
BS425944
|
|
|
|
ATP + L-isoleucine + tRNAMet <=> AMP + diphosphate + L-isoleucyl-tRNALeu
|
6.1.1.5
isoleucine---tRNA ligase
6.1.1.9
valine---tRNA ligase
|
–
–
|
| |
BRENDA:
BR56
KEGG:
R03656
SABIO-RK:
413
|
|
|
|
2-oxobutyrate + oxidized_ferredoxin + CoA <=> propionyl-CoA + reduced_ferredoxin_[iron-sulfur]_cluster + CO2 + H+
|
1.2.7.1
pyruvate synthase
1.2.7.11
2-oxoacid oxidoreductase (ferredoxin)
1.2.7.7
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
|
–
–
–
|
| |
BRENDA:
BS189350
KEGG:
R01199
MetaCyc:
2-OXOBUTYRATE-SYNTHASE-RXN
|
|
|
|
(R)-citramalate <=> citraconate + H2O
|
4.2.1.31
maleate hydratase
4.2.1.35
(R)-2-methylmalate dehydratase
|
–
–
|
| |
BRENDA:
BR415
KEGG:
R03896
MetaCyc:
R-2-METHYLMALATE-DEHYDRATASE-RXN
SABIO-RK:
3641
|
|
|
|
CoA + propionate + ATP <=> propionyl-CoA + diphosphate + AMP
|
6.2.1.1
acetate---CoA ligase
6.2.1.17
propionate---CoA ligase
6.2.1.2
medium-chain acyl-CoA ligase
6.2.1.30
phenylacetate---CoA ligase
6.2.1.36
3-hydroxypropionyl-CoA synthase
6.2.1.44
3-(methylthio)propionyl---CoA ligase
|
–
–
–
–
–
–
|
| |
BRENDA:
BR68
KEGG:
R00925
MetaCyc:
PROPIONATE--COA-LIGASE-RXN
SABIO-RK:
1245
|
|
|
|
L-isoleucine + 2-oxoglutarate <=> L-glutamate + (S)-3-methyl-2-oxopentanoate
|
2.6.1.42
branched-chain-amino-acid transaminase
2.6.1.67
2-aminohexanoate transaminase
|
–
–
|
| |
BRENDA:
BS356522;
BS452227
KEGG:
R02199
MetaCyc:
BRANCHED-CHAINAMINOTRANSFERILEU-RXN
SABIO-RK:
2171;
9086
|
|
|
|
3-methyl-2-oxopentanoate + CoA + oxidized_ferredoxin <=> 2-methylbutanoyl-CoA + CO2 + reduced_ferredoxin
|
1.2.7.7
3-methyl-2-oxobutanoate dehydrogenase (ferredoxin)
|
–
|
| |
BRENDA:
BS359414
|
|
|
|
pyruvate + 2-oxobutyrate <=> 2-aceto-2-hydroxybutyrate + CO2
|
2.2.1.6
acetolactate synthase
|
–
|
| |
BRENDA:
BS432921
|
|
|
|
H+ + 3-methyloxaloacetate <=> 2-oxobutyrate + CO2
|
4.1.1.112
oxaloacetate decarboxylase
|
–
|
| |
BRENDA:
BS390752
KEGG:
R00995
MetaCyc:
RXN-7746
|
|
